Shriek of Vengeance
Target enemy item or support ability with a cost of 4 or less is destroyed, and one of your resources is removed from play.
Shriek of Vengeance is one of the game’s oldest cards, and in my opinion, one of the best. For a very small cost of 1 resource permanently, you can do away with any opposing cost 4 or lower item or support. Although this is card has generally fallen out of favor, but I feel that including this card again in a diverse Quick Match environment can be warranted.